Oregano+BlackSeed
Black Seed Oil

Black Seed Oil and the Immune System: Research Review

Immune cells, inflammation and antioxidant defences in the studies.

Written by Editorial TeamMedically reviewedUpdated on
Laboratory

Key takeaways

  • Thymoquinone modulates immune cells in lab studies.
  • Human trials show changes in some inflammatory markers.
  • Clinical benefits for infections are unproven.

Mechanisms

Thymoquinone reduces inflammatory signalling (NF-κB) and boosts antioxidant enzymes in experimental studies.[1]

Human studies

Clinical reviews report effects on inflammatory markers in various conditions.[2]

Frequently asked questions

Does black seed oil boost immunity?

It modulates immune activity in research, but 'boosting' immunity isn't proven.

The bottom line

Black seed oil affects immune pathways in research. Clinical benefits need more study.

Sources

  1. Darakhshan S, Bidmeshki Pour A, Hosseinzadeh Colagar A, Sisakhtnezhad S. Thymoquinone and its therapeutic potentials. Pharmacol Res. 2015;95-96:138-158.
  2. Tavakkoli A, Mahdian V, Razavi BM, Hosseinzadeh H. Review on clinical trials of black seed (Nigella sativa) and its active constituent, thymoquinone. J Pharmacopuncture. 2017;20(3):179-193.